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PRF Therapy for TMJ & TMD

If your jaw has been sore, stiff or clicking for a while, you may have heard about platelet-rich fibrin, or PRF. It's a treatment made from a small sample of your own blood. At Valley Tongue Tie & Sleep Wellness in Bethlehem, our team may recommend PRF as one part of a broader plan for TMD care, alongside the other treatments that help your jaw joint and muscles settle.

This page explains what PRF is, how it's prepared, what the research says about it for jaw joint problems, and what a visit looks like.

The basics

What Is PRF?

PRF is made by drawing a small amount of your blood and spinning it in a centrifuge. Spinning separates the blood into layers, and the layer used for treatment is rich in platelets, white blood cells and fibrin, a natural protein your body uses to form a healing framework. Platelets carry growth factors that play a role in the body's normal repair process.

From your own blood

Everything in PRF comes from you. There is no donor material and no synthetic drug involved.

Nothing added

Unlike some other blood concentrates, PRF is prepared without anticoagulants or other additives.

Liquid or gel form

PRF can be prepared as an injectable liquid or allowed to set into a gel, depending on how it will be used.

Dentists have used PRF for years to support healing after oral surgery and gum procedures. More recently, an injectable form has been studied for the jaw joint.

PRF and your jaw

How PRF Fits Into TMJ and TMD Care

Most jaw problems are first managed with conservative care: an accurate diagnosis, habit changes, gentle jaw care and, when needed, a custom oral appliance. PRF does not replace those steps. For the right patient, it may be added to support an irritated joint or surrounding tissues while the rest of the plan does its work.

PRF is a co-therapy. It is chosen after a full exam and used alongside other care, not as a stand-alone fix. The goal is to support your body's own healing while the cause of the problem is addressed.

Depending on your exam, PRF may be paired with:

  • A custom orthotic or splint to take pressure off the joint and give the jaw muscles a comfortable place to rest.
  • Habit and posture changes, such as keeping your teeth apart at rest and easing daytime clenching.
  • Orofacial myofunctional therapy to retrain how the tongue, lips and jaw muscles work together.
  • Biostimulation laser therapy or other supportive treatments your provider recommends.
The research

What Studies Say About PRF for the Jaw Joint

Research on PRF for TMD is growing but still young. Several recent systematic reviews have pooled the available clinical trials, most of which tested injectable PRF combined with a joint rinse procedure called arthrocentesis. Overall, these reviews found that adding PRF was associated with less pain and better mouth opening than the comparison treatments for many patients.

PRF is a support for healing, not a cure on its own.

The same reviews are careful to point out the limits: the trials are small, follow-up is often short, and clinics prepare PRF in different ways. That's why we present PRF honestly, as a promising option for some patients that works best as part of a complete plan.

What to expect

What a PRF Visit Looks Like

Every plan is different, but PRF care usually follows a few simple steps:

1

Evaluation

A TMD evaluation looks at your jaw movement, joints and muscles to decide whether PRF makes sense for you.

2

Preparation

A small blood sample is drawn and spun in a centrifuge for a short time to prepare the PRF.

3

Treatment and follow-up

The PRF is placed in the area identified during your exam. Follow-up visits check your progress, and some plans include more than one session.

Because PRF comes from your own blood, there's no foreign material involved. As with any injection, temporary soreness or swelling where it was placed can happen. Your provider will go over aftercare and what to watch for.

Next steps

Is PRF Right for You?

If jaw pain, clicking, locking or a stiff jaw is getting in the way of eating, talking or sleeping, the first step is finding out what's actually going on. At Valley Tongue Tie & Sleep Wellness, we see patients from Bethlehem, Allentown, Easton and across the Lehigh Valley. After your exam, we'll explain whether PRF could be part of your plan and how it would work with your other care. Learn more about TMJ and jaw pain or contact our office to schedule a visit.

FAQ

Common Questions About PRF Therapy

What is PRF?

PRF stands for platelet-rich fibrin. It is made from a small sample of your own blood that is spun in a centrifuge to concentrate platelets, white blood cells and fibrin. Nothing is added, so the material comes entirely from you.

Is PRF the same as PRP?

They are related but not the same. PRP (platelet-rich plasma) is usually prepared with an anticoagulant added to the blood. PRF is prepared without anticoagulants or other additives, which is why it is described as fully autologous, meaning it comes only from your own body.

How is PRF used for TMJ and TMD?

For jaw joint problems, PRF is usually prepared in a liquid (injectable) form and placed in or around the area identified during your exam. Most research has studied it alongside other care, such as a joint rinse called arthrocentesis, rather than on its own.

Does PRF cure TMD?

No single treatment cures TMD. Research reviews suggest PRF may help reduce pain and improve jaw opening for some patients when it is added to other care, but study sizes are small and methods vary. We treat it as one supporting piece of a complete plan.

Will I still need a splint or other treatment?

Often, yes. PRF is typically used alongside other TMD care, such as a custom orthotic, habit changes, jaw exercises or myofunctional therapy, so the joint and muscles get support while they settle.

Does PRF hurt?

The blood draw feels like a routine blood test. You may feel pressure or brief soreness where the PRF is placed, and some temporary soreness or swelling afterward is possible. Your provider will talk you through what to expect and how to stay comfortable.

Sources

References

  1. Dohan DM, Choukroun J, Diss A, et al. (2006). Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 101(3), e37–e44. doi.org/10.1016/j.tripleo.2005.07.008
  2. Miron RJ, Zucchelli G, Pikos MA, et al. (2017). Use of platelet-rich fibrin in regenerative dentistry: a systematic review. Clinical Oral Investigations, 21(6), 1913–1927. doi.org/10.1007/s00784-017-2133-z
  3. Nagori SA, Gopalakrishnan V, Rangarajan H, et al. (2024). Does intra-articular injection of platelet-rich plasma/platelet-rich fibrin improve outcomes after temporomandibular joint arthrocentesis? A systematic review and meta-analysis. British Journal of Oral and Maxillofacial Surgery, 62(8), 676–684. doi.org/10.1016/j.bjoms.2024.06.007
  4. Nemeth A, Gurgel BV, Lowenstein A, et al. (2024). Does liquid/injectable platelet-rich fibrin help in the arthrocentesis treatment of temporomandibular joint disorder compared to other infusion options? A systematic review of randomized clinical trials. Bioengineering, 11(3), 247. doi.org/10.3390/bioengineering11030247
  5. de Araújo JSG, de Oliveira da Rosa WL, Meirelles LAD, et al. (2026). Effectiveness of platelet-rich fibrin for temporomandibular disorders management: a systematic review and meta-analysis. Oral Diseases, 32(2), 288–299. doi.org/10.1111/odi.70089
  6. National Institute of Dental and Craniofacial Research (NIDCR). Temporomandibular Disorders (TMD). nidcr.nih.gov/health-info/tmd

This page is for patient education and does not replace a clinical exam. Whether PRF is appropriate depends on your diagnosis and health history. Schedule an evaluation with our Bethlehem office to talk through your options.

Curious whether PRF could help your jaw?

Call Valley Tongue Tie & Sleep Wellness in Bethlehem to schedule a TMD evaluation. We serve patients throughout Bethlehem and the Lehigh Valley.

(484) 767-7782
TMJ & jaw pain TMD care Contact

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LINKS TO THIRD PARTY SITES


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USE OF COMMUNICATION SERVICES


This Practice website may contain bulletin board services, chat areas, news groups, forums, communities, personal web pages, calendars, and/or other message or communication facilities designed to enable you to communicate with the public at large or with a group (collectively, "Communication Services"), you agree to use the Communication Services only to post, send and receive messages and material that are proper and related to the particular Communication Service.


By way of example, and not as a limitation, you agree that when using a Communication Service, you will not:


  • Defame, abuse, harass, stalk, threaten or otherwise violate the legal rights (such as rights of privacy and publicity) of others.
  • Publish, post, upload, distribute or disseminate any inappropriate, profane, defamatory, infringing, obscene, indecent or unlawful topic, name, material or information.
  • Upload files that contain software or other material protected by intellectual property laws (or by rights of privacy of publicity) unless you own or control the rights thereto or have received all necessary consents.
  • Upload files that contain viruses, corrupted files, or any other similar software or programs that may damage the operation of another's computer.
  • Advertise or offer to sell or buy any goods or services for any business purpose, unless such Communication Service specifically allows such messages.
  • Conduct or forward surveys, contests, pyramid schemes or chain letters.
  • Download any file posted by another user of a Communication Service that you know, or reasonably should know, cannot be legally distributed in such manner.
  • Falsify or delete any author attributions, legal or other proper notices or proprietary designations or labels of the origin or source of software or other material contained in a file that is uploaded.
  • Restrict or inhibit any other user from using and enjoying the Communication Services.
  • Violate any code of conduct or other guidelines which may be applicable for any particular Communication Service.
  • Harvest or otherwise collect information about others, including e-mail addresses, without their consent.
  • Violate any applicable laws or regulations.


This Practice has no obligation to monitor the Communication Services. However, this Practice reserves the right to review materials posted to a Communication Service and to remove any materials in its sole discretion. This Practice reserves the right to terminate your access to any or all of the Communication Services at any time without notice for any reason whatsoever.Materials uploaded to a Communication Service may be subject to posted limitations on usage, reproduction and/or dissemination. You are responsible for adhering to such limitations if you download the materials.


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THE INFORMATION, SOFTWARE, PRODUCTS, AND SERVICES INCLUDED IN OR AVAILABLE THROUGH THIS PRACTICE WEBSITE MAY INCLUDE INACCURACIES OR TYPOGRAPHICAL ERRORS. CHANGES ARE PERIODICALLY ADDED TO THE INFORMATION HEREIN. THIS PRACTICE AND/OR ITS SUPPLIERS MAY MAKE IMPROVEMENTS AND/OR CHANGES IN THIS PRACTICE WEBSITE AT ANY TIME. ADVICE RECEIVED VIA THIS PRACTICE WEBSITE SHOULD NOT BE RELIED UPON FOR PERSONAL, MEDICAL, LEGAL OR FINANCIAL DECISIONS AND YOU SHOULD CONSULT AN APPROPRIATE PROFESSIONAL FOR SPECIFIC ADVICE TAILORED TO YOUR SITUATION.THIS PRACTICE AND/OR ITS SUPPLIERS MAKE NO REPRESENTATIONS ABOUT THE SUITABILITY, RELIABILITY, AVAILABILITY, TIMELINESS, AND ACCURACY OF THE INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS CONTAINED ON THIS PRACTICE WEBSITE FOR ANY PURPOSE. TO THE MAXIMUM EXTENT PERMITTED BY APPLICABLE LAW, ALL SUCH INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS ARE PROVIDED "AS IS" WITHOUT WARRANTY OR CONDITION OF ANY KIND. THIS PRACTICE AND/OR ITS SUPPLIERS HEREBY DISCLAIM ALL WARRANTIES AND CONDITIONS WITH REGARD TO THIS INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS, INCLUDING ALL IMPLIED WARRANTIES OR CONDITIONS OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, TITLE AND NON-INFRINGEMENT.TO THE MAXIMUM EXTENT PERMITTED BY APPLICABLE LAW, IN NO EVENT SHALL THIS PRACTICE AND/OR ITS SUPPLIERS BE LIABLE FOR ANY DIRECT, INDIRECT, PUNITIVE, INCIDENTAL, SPECIAL, CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER INCLUDING, WITHOUT LIMITATION, DAMAGES FOR LOSS OF USE, DATA OR PROFITS, ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE USE OR PERFORMANCE OF THIS PRACTICE WEBSITE, WITH THE DELAY OR INABILITY TO USE THIS PRACTICE WEBSITE OR RELATED SERVICES, THE PROVISION OF OR FAILURE TO PROVIDE SERVICES, OR FOR ANY INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS OBTAINED THROUGH THIS PRACTICE WEBSITE, OR OTHERWISE ARISING OUT OF THE USE OF THIS PRACTICE WEBSITE, WHETHER BASED ON CONTRACT, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, EVEN IF THIS PRACTICE OR ANY OF ITS SUPPLIERS HAS BEEN ADVISED OF THE POSSIBILITY OF DAMAGES. BECAUSE SOME STATES/JURISDICTIONS DO NOT ALLOW THE EXCLUSION OR LIMITATION OF LIABILITY FOR CONSEQUENTIAL OR INCIDENTAL DAMAGES, THE ABOVE LIMITATION MAY NOT APPLY TO YOU. IF YOU ARE DISSATISFIED WITH ANY PORTION OF THIS PRACTICE WEBSITE, OR WITH ANY OF THESE TERMS OF USE, YOUR SOLE AND EXCLUSIVE REMEDY IS TO DISCONTINUE USING THIS PRACTICE WEBSITE.


COPYRIGHT AND TRADEMARK NOTICES


All contents of this website are Copyright © 2023 Valley Tongue Tie & Sleep Wellness Center. All Rights Reserved. All logos are trademarks and service marks of Valley Tongue Tie & Sleep Wellness Center. All other trademarks, service marks and logos used in this website are the property of their respective owners.


TRADEMARKS


The names of actual companies and products mentioned herein may be the trademarks of their respective owners.The example companies, organizations, products, people and events depicted herein are fictitious. No association with any real company, organization, product, person, or event is intended or should be inferred.Any rights not expressly granted herein are reserved.

NOTICES


Please contact us by phone at (484) 767-7782 or by mail at 1424 Broadway Bethlehem, PA 18015

TERMS & CONDITIONS

This Practice website is offered to you conditioned on your acceptance without modification of the terms, conditions, and notices contained herein. Your use of this Practice website constitutes your agreement to all such terms, conditions, and notices.


MODIFICATION OF THESE TERMS OF USE


This Practice reserves the right to change the terms, conditions, and notices under which this Practice website is offered, including but not limited to the charges associated with the use of this Practice website

LINKS TO THIRD PARTY SITES


This Practice website may contain links to other websites ("Linked Sites"). The Linked Sites are not under the control of this Practice and this Practice is not responsible for the contents of any Linked Site, including without limitation any link contained in a Linked Site, or any changes or updates to a Linked Site. This Practice is not responsible for webcasting or any other form of transmission received from any Linked Site. This Practice is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement by this Practice of the site or any association with its operators.

NO UNLAWFUL OR PROHIBITED USE


As a condition of your use of this Practice website, you warrant to this Practice that you will not use this Practice website for any purpose that is unlawful or prohibited by these terms, conditions, and notices. You may not use this Practice website in any manner which could damage, disable, overburden, or impair this Practice website or interfere with any other party's use and enjoyment of this Practice website. You may not obtain or attempt to obtain any materials or information through any means not intentionally made available or provided for through this Practice websites.

USE OF COMMUNICATION SERVICES


This Practice website may contain bulletin board services, chat areas, news groups, forums, communities, personal web pages, calendars, and/or other message or communication facilities designed to enable you to communicate with the public at large or with a group (collectively, "Communication Services"), you agree to use the Communication Services only to post, send and receive messages and material that are proper and related to the particular Communication Service.


By way of example, and not as a limitation, you agree that when using a Communication Service, you will not:


• Defame, abuse, harass, stalk, threaten or otherwise violate the legal rights (such as rights of privacy and publicity) of others.

• Publish, post, upload, distribute or disseminate any inappropriate, profane, defamatory, infringing, obscene, indecent or unlawful topic, name, material or information.

• Upload files that contain software or other material protected by intellectual property laws (or by rights of privacy of publicity) • unless you own or control the rights thereto or have received all necessary consents.

• Upload files that contain viruses, corrupted files, or any other similar software or programs that may damage the operation of another's • computer.

• Advertise or offer to sell or buy any goods or services for any business purpose, unless such Communication Service specifically allows such messages.

• Conduct or forward surveys, contests, pyramid schemes or chain letters.

• Download any file posted by another user of a Communication Service that you know, or reasonably should know, cannot be legally • distributed in such manner.

• Falsify or delete any author attributions, legal or other proper notices or proprietary designations or labels of the origin or source of software or other material contained in a file that is uploaded.

• Restrict or inhibit any other user from using and enjoying the Communication Services.

• Violate any code of conduct or other guidelines which may be applicable for any particular Communication Service.

• Harvest or otherwise collect information about others, including e-mail addresses, without their consent.

• Violate any applicable laws or regulations.


This Practice has no obligation to monitor the Communication Services. However, this Practice reserves the right to review materials posted to a Communication Service and to remove any materials in its sole discretion. This Practice reserves the right to terminate your access to any or all of the Communication Services at any time without notice for any reason whatsoever.Materials uploaded to a Communication Service may be subject to posted limitations on usage, reproduction and/or dissemination. You are responsible for adhering to such limitations if you download the materials.

LIABILITY DISCLAIMER


THE INFORMATION, SOFTWARE, PRODUCTS, AND SERVICES INCLUDED IN OR AVAILABLE THROUGH THIS PRACTICE WEBSITE MAY INCLUDE INACCURACIES OR TYPOGRAPHICAL ERRORS. CHANGES ARE PERIODICALLY ADDED TO THE INFORMATION HEREIN. THIS PRACTICE AND/OR ITS SUPPLIERS MAY MAKE IMPROVEMENTS AND/OR CHANGES IN THIS PRACTICE WEBSITE AT ANY TIME. ADVICE RECEIVED VIA THIS PRACTICE WEBSITE SHOULD NOT BE RELIED UPON FOR PERSONAL, MEDICAL, LEGAL OR FINANCIAL DECISIONS AND YOU SHOULD CONSULT AN APPROPRIATE PROFESSIONAL FOR SPECIFIC ADVICE TAILORED TO YOUR SITUATION.THIS PRACTICE AND/OR ITS SUPPLIERS MAKE NO REPRESENTATIONS ABOUT THE SUITABILITY, RELIABILITY, AVAILABILITY, TIMELINESS, AND ACCURACY OF THE INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS CONTAINED ON THIS PRACTICE WEBSITE FOR ANY PURPOSE. TO THE MAXIMUM EXTENT PERMITTED BY APPLICABLE LAW, ALL SUCH INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS ARE PROVIDED "AS IS" WITHOUT WARRANTY OR CONDITION OF ANY KIND. THIS PRACTICE AND/OR ITS SUPPLIERS HEREBY DISCLAIM ALL WARRANTIES AND CONDITIONS WITH REGARD TO THIS INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS, INCLUDING ALL IMPLIED WARRANTIES OR CONDITIONS OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, TITLE AND NON-INFRINGEMENT.TO THE MAXIMUM EXTENT PERMITTED BY APPLICABLE LAW, IN NO EVENT SHALL THIS PRACTICE AND/OR ITS SUPPLIERS BE LIABLE FOR ANY DIRECT, INDIRECT, PUNITIVE, INCIDENTAL, SPECIAL, CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER INCLUDING, WITHOUT LIMITATION, DAMAGES FOR LOSS OF USE, DATA OR PROFITS, ARISING OUT OF OR IN ANY WAY CONNECTED WITH THE USE OR PERFORMANCE OF THIS PRACTICE WEBSITE, WITH THE DELAY OR INABILITY TO USE THIS PRACTICE WEBSITE OR RELATED SERVICES, THE PROVISION OF OR FAILURE TO PROVIDE SERVICES, OR FOR ANY INFORMATION, SOFTWARE, PRODUCTS, SERVICES AND RELATED GRAPHICS OBTAINED THROUGH THIS PRACTICE WEBSITE, OR OTHERWISE ARISING OUT OF THE USE OF THIS PRACTICE WEBSITE, WHETHER BASED ON CONTRACT, TORT, NEGLIGENCE, STRICT LIABILITY OR OTHERWISE, EVEN IF THIS PRACTICE OR ANY OF ITS SUPPLIERS HAS BEEN ADVISED OF THE POSSIBILITY OF DAMAGES. BECAUSE SOME STATES/JURISDICTIONS DO NOT ALLOW THE EXCLUSION OR LIMITATION OF LIABILITY FOR CONSEQUENTIAL OR INCIDENTAL DAMAGES, THE ABOVE LIMITATION MAY NOT APPLY TO YOU. IF YOU ARE DISSATISFIED WITH ANY PORTION OF THIS PRACTICE WEBSITE, OR WITH ANY OF THESE TERMS OF USE, YOUR SOLE AND EXCLUSIVE REMEDY IS TO DISCONTINUE USING THIS PRACTICE WEBSITE.


COPYRIGHT AND TRADEMARK NOTICES


All contents of this website are Copyright © 2023 Valley Tongue Tie & Sleep Wellness Center. All Rights Reserved. All logos are trademarks and service marks of Valley Tongue Tie & Sleep Wellness Center. All other trademarks, service marks and logos used in this website are the property of their respective owners.

TRADEMARKS

The names of actual companies and products mentioned herein may be the trademarks of their respective owners.The example companies, organizations, products, people and events depicted herein are fictitious. No association with any real company, organization, product, person, or event is intended or should be inferred.Any rights not expressly granted herein are reserved.

NOTICES

Please contact us by phone at (484) 767-7782 or by mail at 1424 Broadway Bethlehem, PA 18015

ACCESSIBILITY STATEMENT

We are committed to providing a website that is accessible to individuals with disabilities, in conformance with the Web Content Accessibility Guidelines (WCAG) 2.1, Level A & AA.


To this end, we regularly test our website in accordance with best practices, using automated and manual testing and with the assistance of accessibility consultant eSSENTIAL Accessibility which is supported by a diverse team of accessibility professionals including users of assistive technologies. We also make available an assistive CX technology application which our customers who have trouble typing, gesturing, moving a mouse, or reading can use for additional accessibility, however it is not required to use our website. The application is free to download and it incorporates tools such as mouse and keyboard replacements, voice recognition, speech enablement, hands-free/touch-free navigation, and more.


We welcome your feedback. If you encounter any accessibility barriers or otherwise have difficulty using our website due your disability, please contact our office and we will make any necessary changes.

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